PHLDB2-KCNAB1 Fusion FISH Probe
The PHLDB2-KCNAB1 Fusion FISH Probe is used to confirm a fusion of the PHLDB2 and KCNAB1 genes. The fusion of the PHLDB2 and KCNAB1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHLDB2-KCNAB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-RERE | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-REOR | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-REGO | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-REGR | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-REAQ | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-ORRE | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-OROR | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-ORGO | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GORE | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GOOR | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GOGO | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GOGR | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GRRE | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GROR | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GRGO | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GRGR | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-AQRE | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-AQOR | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-AQGO | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-AQGR | 20 (40 μL) | 200 μL |
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| PHLDB2-KCNAB1-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNAB1 Gene Summary
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Apr 2015]
Gene Name: Potassium Voltage-gated Channel Subfamily A Member Regulatory Beta Subunit 1
Chromosome: CHR3: 155838336 -156256927
Locus: 3q25.31
PHLDB2 Gene Summary
The Pleckstrin Homology Like Domain Family B Member 2 (PHLDB2) gene is located on chr3 :111451326-111695364 at 3q13.2.
Gene Name: Pleckstrin Homology Like Domain Family B Member 2
Chromosome: CHR3: 111451326 -111695364
Locus: 3q13.2
Gene Diseases
The PHLDB2 KCNAB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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