PHIP-MYO6 Fusion FISH Probe
The PHIP-MYO6 Fusion FISH Probe is used to confirm a fusion of the PHIP and MYO6 genes. The fusion of the PHIP and MYO6 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHIP-MYO6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-RERE | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-REOR | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-REGO | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-REGR | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-REAQ | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-ORRE | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-OROR | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-ORGO | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GORE | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GOOR | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GOGO | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GOGR | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GRRE | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GROR | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GRGO | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GRGR | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-AQRE | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-AQOR | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-AQGO | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-AQGR | 20 (40 μL) | 200 μL |
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| PHIP-MYO6-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO6 Gene Summary
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Gene Name: Myosin VI
Chromosome: CHR6: 76458908 -76629254
Locus: 6q14.1
PHIP Gene Summary
This gene encodes a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. The encoded protein may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients. [provided by RefSeq, Oct 2016]
Gene Name: Pleckstrin Homology Domain Interacting Protein
Chromosome: CHR6: 79644135 -79788011
Locus: 6q14.1
Gene Diseases
The PHIP MYO6 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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