PHF21A-ARHGAP1 Fusion FISH Probe
The PHF21A-ARHGAP1 Fusion FISH Probe is used to confirm a fusion of the PHF21A and ARHGAP1 genes. The fusion of the PHF21A and ARHGAP1 genes has been associated with Bladder Urothelial Carcinoma, and Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHF21A-ARHGAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-RERE | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-REOR | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-REGO | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-REGR | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-OROR | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GORE | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GROR | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PHF21A-ARHGAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGAP1 Gene Summary
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members. [provided by RefSeq, Aug 2012]
Gene Name: Rho GTPase Activating Protein 1
Chromosome: CHR11: 46698631 -46722120
Locus: 11p11.2
PHF21A Gene Summary
The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]).[supplied by OMIM, Nov 2010]
Gene Name: PHD Finger Protein 21A
Chromosome: CHR11: 45950869 -46142985
Locus: 11p11.2
Gene Diseases
The PHF21A ARHGAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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