PHF21A-ACSL6 Fusion FISH Probe
The PHF21A-ACSL6 Fusion FISH Probe is used to confirm a fusion of the PHF21A and ACSL6 genes. The fusion of the PHF21A and ACSL6 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHF21A-ACSL6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-RERE | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-REOR | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-REGO | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-REGR | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-REAQ | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-ORRE | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-OROR | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-ORGO | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GORE | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GOOR | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GOGO | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GOGR | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GRRE | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GROR | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GRGO | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GRGR | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-AQRE | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-AQOR | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-AQGO | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-AQGR | 20 (40 μL) | 200 μL |
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| PHF21A-ACSL6-20-AQAQ | 20 (40 μL) | 200 μL |
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ACSL6 Gene Summary
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]
Gene Name: Acyl-CoA Synthetase Long Chain Family Member 6
Chromosome: CHR5: 131285666 -131347761
Locus: 5q31.1
PHF21A Gene Summary
The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]).[supplied by OMIM, Nov 2010]
Gene Name: PHD Finger Protein 21A
Chromosome: CHR11: 45950869 -46142985
Locus: 11p11.2
Gene Diseases
The PHF21A ACSL6 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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