PHF12-LIG3 Fusion FISH Probe
The PHF12-LIG3 Fusion FISH Probe is used to confirm a fusion of the PHF12 and LIG3 genes. The fusion of the PHF12 and LIG3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHF12-LIG3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-RERE | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-REOR | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-REGO | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-REGR | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-REAQ | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-ORRE | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-OROR | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-ORGO | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GORE | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GOOR | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GOGO | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GOGR | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GRRE | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GROR | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GRGO | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GRGR | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-AQRE | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-AQOR | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-AQGO | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-AQGR | 20 (40 μL) | 200 μL |
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| PHF12-LIG3-20-AQAQ | 20 (40 μL) | 200 μL |
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LIG3 Gene Summary
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: DNA Ligase 3
Chromosome: CHR17: 33307516 -33332088
Locus: 17q12
PHF12 Gene Summary
The PHD Finger Protein 12 (PHF12) gene is located on chr17 :27232270-27278508 at 17q11.2.
Gene Name: PHD Finger Protein 12
Chromosome: CHR17: 27232270 -27278508
Locus: 17q11.2
Gene Diseases
The PHF12 LIG3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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