PHC2-CSMD2 Fusion FISH Probe
The PHC2-CSMD2 Fusion FISH Probe is used to confirm a fusion of the PHC2 and CSMD2 genes. The fusion of the PHC2 and CSMD2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHC2-CSMD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-RERE | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-REOR | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-REGO | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-REGR | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-REAQ | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-ORRE | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-OROR | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-ORGO | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GORE | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GOOR | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GOGO | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GOGR | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GRRE | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GROR | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GRGO | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GRGR | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-AQRE | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-AQOR | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-AQGO | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-AQGR | 20 (40 μL) | 200 μL |
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| PHC2-CSMD2-20-AQAQ | 20 (40 μL) | 200 μL |
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PHC2 Gene Summary
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Polyhomeotic Homolog 2
Chromosome: CHR1: 33789223 -33841194
Locus: 1p35.1
CSMD2 Gene Summary
The protein encoded by this gene is thought to be involved in the control of complement. Defects in this gene have been associated with schizophrenia. This gene may act as a tumor suppressor for colorectal cancer. [provided by RefSeq, Mar 2017]
Gene Name: CUB And Sushi Multiple Domains 2
Chromosome: CHR1: 33979608 -34631443
Locus: 1p35.1
Gene Diseases
The PHC2 CSMD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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