PHB-LSM1 Fusion FISH Probe
The PHB-LSM1 Fusion FISH Probe is used to confirm a fusion of the PHB and LSM1 genes. The fusion of the PHB and LSM1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHB-LSM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-RERE | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-REOR | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-REGO | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-REGR | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-REAQ | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-ORRE | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-OROR | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-ORGO | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GORE | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GOOR | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GOGO | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GOGR | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GRRE | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GROR | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GRGO | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GRGR | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-AQRE | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-AQOR | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-AQGO | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-AQGR | 20 (40 μL) | 200 μL |
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| PHB-LSM1-20-AQAQ | 20 (40 μL) | 200 μL |
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PHB Gene Summary
This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Prohibitin
Chromosome: CHR17: 47481419 -47492242
Locus: 17q21.33
LSM1 Gene Summary
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011]
Gene Name: LSM1 Homolog, MRNA Degradation Associated
Chromosome: CHR8: 38020858 -38034026
Locus: 8p11.23
Gene Diseases
The PHB LSM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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