PHACTR3-BCAS1 Fusion FISH Probe
The PHACTR3-BCAS1 Fusion FISH Probe is used to confirm a fusion of the PHACTR3 and BCAS1 genes. The fusion of the PHACTR3 and BCAS1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PHACTR3-BCAS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PHACTR3-BCAS1-20-AQAQ | 20 (40 μL) | 200 μL |
|
BCAS1 Gene Summary
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016]
Gene Name: Breast Carcinoma Amplified Sequence 1
Chromosome: CHR20: 52560078 -52687304
Locus: 20q13.2
PHACTR3 Gene Summary
This gene encodes a member of the phosphatase and actin regulator protein family. The encoded protein is associated with the nuclear scaffold in proliferating cells, and binds to actin and the catalytic subunit of protein phosphatase-1, suggesting that it functions as a regulatory subunit of protein phosphatase-1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Phosphatase And Actin Regulator 3
Chromosome: CHR20: 58152563 -58422766
Locus: 20q13.32-q13.33
Gene Diseases
The PHACTR3 BCAS1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|