PHACTR2-PLAGL1 Fusion FISH Probe
The PHACTR2-PLAGL1 Fusion FISH Probe is used to confirm a fusion of the PHACTR2 and PLAGL1 genes. The fusion of the PHACTR2 and PLAGL1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHACTR2-PLAGL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-RERE | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-REOR | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-REGO | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-REGR | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-REAQ | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-ORRE | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-OROR | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-ORGO | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GORE | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GOOR | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GOGO | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GOGR | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GRRE | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GROR | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GRGO | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GRGR | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-AQRE | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-AQOR | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-AQGO | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-AQGR | 20 (40 μL) | 200 μL |
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| PHACTR2-PLAGL1-20-AQAQ | 20 (40 μL) | 200 μL |
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PLAGL1 Gene Summary
This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015]
Gene Name: PLAG1 Like Zinc Finger 1
Chromosome: CHR6: 144261436 -144385735
Locus: 6q24.2
PHACTR2 Gene Summary
The Phosphatase And Actin Regulator 2 (PHACTR2) gene is located on chr6 :143929316-144152322 at 6q24.2.
Gene Name: Phosphatase And Actin Regulator 2
Chromosome: CHR6: 143929316 -144152322
Locus: 6q24.2
Gene Diseases
The PHACTR2 PLAGL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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