PHACTR1-BCL11A Fusion FISH Probe
The PHACTR1-BCL11A Fusion FISH Probe is used to confirm a fusion of the PHACTR1 and BCL11A genes. The fusion of the PHACTR1 and BCL11A genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHACTR1-BCL11A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-RERE | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-REOR | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-REGO | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-REGR | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-REAQ | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-ORRE | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-OROR | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-ORGO | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GORE | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GOOR | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GOGO | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GOGR | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GRRE | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GROR | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GRGO | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GRGR | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-AQRE | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-AQOR | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-AQGO | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-AQGR | 20 (40 μL) | 200 μL |
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| PHACTR1-BCL11A-20-AQAQ | 20 (40 μL) | 200 μL |
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BCL11A Gene Summary
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: B-cell CLL/lymphoma 11A
Chromosome: CHR2: 60678301 -60780633
Locus: 2p16.1
PHACTR1 Gene Summary
The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
Gene Name: Phosphatase And Actin Regulator 1
Chromosome: CHR6: 12717036 -13288075
Locus: 6p24.1
Gene Diseases
The PHACTR1 BCL11A Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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