PGD-CAMTA1 Fusion FISH Probe
The PGD-CAMTA1 Fusion FISH Probe is used to confirm a fusion of the PGD and CAMTA1 genes. The fusion of the PGD and CAMTA1 genes has been associated with Glioblastoma Multiforme, and Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PGD-CAMTA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-RERE | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-REOR | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-REGO | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-REGR | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-REAQ | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-ORRE | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-OROR | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-ORGO | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GORE | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GOOR | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GOGO | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GOGR | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GRRE | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GROR | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GRGO | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GRGR | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-AQRE | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-AQOR | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-AQGO | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-AQGR | 20 (40 μL) | 200 μL |
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| PGD-CAMTA1-20-AQAQ | 20 (40 μL) | 200 μL |
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PGD Gene Summary
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Gene Name: Phosphogluconate Dehydrogenase
Chromosome: CHR1: 10459084 -10480201
Locus: 1p36.22
CAMTA1 Gene Summary
The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. [provided by RefSeq, Mar 2017]
Gene Name: Calmodulin Binding Transcription Activator 1
Chromosome: CHR1: 6845383 -7829766
Locus: 1p36.31-p36.23
Gene Diseases
The PGD CAMTA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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