PEX14-EPHA2 Fusion FISH Probe
The PEX14-EPHA2 Fusion FISH Probe is used to confirm a fusion of the PEX14 and EPHA2 genes. The fusion of the PEX14 and EPHA2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PEX14-EPHA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-RERE | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-REOR | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-REGO | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-REGR | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-REAQ | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-ORRE | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-OROR | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-ORGO | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GORE | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GOOR | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GOGO | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GOGR | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GRRE | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GROR | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GRGO | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GRGR | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-AQRE | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-AQOR | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-AQGO | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-AQGR | 20 (40 μL) | 200 μL |
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| PEX14-EPHA2-20-AQAQ | 20 (40 μL) | 200 μL |
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EPHA2 Gene Summary
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]
Gene Name: EPH Receptor A2
Chromosome: CHR1: 16450831 -16482582
Locus: 1p36.13
PEX14 Gene Summary
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Peroxisomal Biogenesis Factor 14
Chromosome: CHR1: 10535002 -10690815
Locus: 1p36.22
Gene Diseases
The PEX14 EPHA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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