SEARCH OUR PRODUCT CATALOG

PEX14-EPHA2 Fusion FISH Probe

The PEX14-EPHA2 Fusion FISH Probe is used to confirm a fusion of the PEX14 and EPHA2 genes. The fusion of the PEX14 and EPHA2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PEX14-EPHA2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PEX14-EPHA2-20-RERE 20 (40 μL) 200 μL
PEX14-EPHA2-20-REOR 20 (40 μL) 200 μL
PEX14-EPHA2-20-REGO 20 (40 μL) 200 μL
PEX14-EPHA2-20-REGR 20 (40 μL) 200 μL
PEX14-EPHA2-20-REAQ 20 (40 μL) 200 μL
PEX14-EPHA2-20-ORRE 20 (40 μL) 200 μL
PEX14-EPHA2-20-OROR 20 (40 μL) 200 μL
PEX14-EPHA2-20-ORGO 20 (40 μL) 200 μL
PEX14-EPHA2-20-ORAQ 20 (40 μL) 200 μL
PEX14-EPHA2-20-GORE 20 (40 μL) 200 μL
PEX14-EPHA2-20-GOOR 20 (40 μL) 200 μL
PEX14-EPHA2-20-GOGO 20 (40 μL) 200 μL
PEX14-EPHA2-20-GOGR 20 (40 μL) 200 μL
PEX14-EPHA2-20-GOAQ 20 (40 μL) 200 μL
PEX14-EPHA2-20-GRRE 20 (40 μL) 200 μL
PEX14-EPHA2-20-GROR 20 (40 μL) 200 μL
PEX14-EPHA2-20-GRGO 20 (40 μL) 200 μL
PEX14-EPHA2-20-GRGR 20 (40 μL) 200 μL
PEX14-EPHA2-20-GRAQ 20 (40 μL) 200 μL
PEX14-EPHA2-20-AQRE 20 (40 μL) 200 μL
PEX14-EPHA2-20-AQOR 20 (40 μL) 200 μL
PEX14-EPHA2-20-AQGO 20 (40 μL) 200 μL
PEX14-EPHA2-20-AQGR 20 (40 μL) 200 μL
PEX14-EPHA2-20-AQAQ 20 (40 μL) 200 μL

EPHA2 Gene Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]

Gene Name: EPH Receptor A2

Chromosome: CHR1: 16450831 -16482582

Locus: 1p36.13

PEX14 Gene Summary

This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]

Gene Name: Peroxisomal Biogenesis Factor 14

Chromosome: CHR1: 10535002 -10690815

Locus: 1p36.22

Gene Diseases

The PEX14 EPHA2 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.