PER3-CELA2A Fusion FISH Probe
The PER3-CELA2A Fusion FISH Probe is used to confirm a fusion of the PER3 and CELA2A genes. The fusion of the PER3 and CELA2A genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PER3-CELA2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-RERE | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-REOR | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-REGO | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-REGR | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-REAQ | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-ORRE | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-OROR | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-ORGO | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GORE | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GOOR | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GOGO | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GOGR | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GRRE | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GROR | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GRGO | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GRGR | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-AQRE | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-AQOR | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-AQGO | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-AQGR | 20 (40 μL) | 200 μL |
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| PER3-CELA2A-20-AQAQ | 20 (40 μL) | 200 μL |
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PER3 Gene Summary
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]
Gene Name: Period Circadian Regulator 3
Chromosome: CHR1: 7844762 -7905237
Locus: 1p36.23
CELA2A Gene Summary
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, May 2009]
Gene Name: Chymotrypsin Like Elastase Family Member 2A
Chromosome: CHR1: 15783222 -15798586
Locus: 1p36.21
Gene Diseases
The PER3 CELA2A Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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