PEPD-SKAP1 Fusion FISH Probe
The PEPD-SKAP1 Fusion FISH Probe is used to confirm a fusion of the PEPD and SKAP1 genes. The fusion of the PEPD and SKAP1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PEPD-SKAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PEPD-SKAP1-20-AQAQ | 20 (40 μL) | 200 μL |
|
PEPD Gene Summary
This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Gene Name: Peptidase D
Chromosome: CHR19: 33877854 -34012799
Locus: 19q13.11
SKAP1 Gene Summary
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]
Gene Name: Src Kinase Associated Phosphoprotein 1
Chromosome: CHR17: 46210801 -46507594
Locus: 17q21.32
Gene Diseases
The PEPD SKAP1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|