PELI1-ACTG2 Fusion FISH Probe
The PELI1-ACTG2 Fusion FISH Probe is used to confirm a fusion of the PELI1 and ACTG2 genes. The fusion of the PELI1 and ACTG2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PELI1-ACTG2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-RERE | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-REOR | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-REGO | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-REGR | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-REAQ | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-ORRE | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-OROR | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-ORGO | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GORE | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GOOR | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GOGO | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GOGR | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GRRE | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GROR | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GRGO | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GRGR | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-AQRE | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-AQOR | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-AQGO | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-AQGR | 20 (40 μL) | 200 μL |
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| PELI1-ACTG2-20-AQAQ | 20 (40 μL) | 200 μL |
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ACTG2 Gene Summary
Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]
Gene Name: Actin, Gamma 2, Smooth Muscle, Enteric
Chromosome: CHR2: 74120092 -74146780
Locus: 2p13.1
PELI1 Gene Summary
The Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) gene is located on chr2 :64319785-64371605 at 2p14.
Gene Name: Pellino E3 Ubiquitin Protein Ligase 1
Chromosome: CHR2: 64319785 -64371605
Locus: 2p14
Gene Diseases
The PELI1 ACTG2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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