PEA15-SIAE Fusion FISH Probe
The PEA15-SIAE Fusion FISH Probe is used to confirm a fusion of the PEA15 and SIAE genes. The fusion of the PEA15 and SIAE genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PEA15-SIAE-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-RERE | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-REOR | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-REGO | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-REGR | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-REAQ | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-ORRE | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-OROR | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-ORGO | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-ORAQ | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GORE | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GOOR | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GOGO | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GOGR | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GOAQ | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GRRE | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GROR | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GRGO | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GRGR | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-GRAQ | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-AQRE | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-AQOR | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-AQGO | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-AQGR | 20 (40 μL) | 200 μL |
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| PEA15-SIAE-20-AQAQ | 20 (40 μL) | 200 μL |
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PEA15 Gene Summary
This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: Proliferation And Apoptosis Adaptor Protein 15
Chromosome: CHR1: 160175124 -160185162
Locus: 1q23.2
SIAE Gene Summary
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Sialic Acid Acetylesterase
Chromosome: CHR11: 124505684 -124546199
Locus: 11q24.2
Gene Diseases
The PEA15 SIAE Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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