PDZRN3-TMC1 Fusion FISH Probe
The PDZRN3-TMC1 Fusion FISH Probe is used to confirm a fusion of the PDZRN3 and TMC1 genes. The fusion of the PDZRN3 and TMC1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDZRN3-TMC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-RERE | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-REOR | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-REGO | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-REGR | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-REAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-ORRE | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-OROR | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-ORGO | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GORE | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GOOR | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GOGO | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GOGR | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GRRE | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GROR | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GRGO | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GRGR | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-AQRE | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-AQOR | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-AQGO | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-AQGR | 20 (40 μL) | 200 μL |
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| PDZRN3-TMC1-20-AQAQ | 20 (40 μL) | 200 μL |
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PDZRN3 Gene Summary
This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: PDZ Domain Containing Ring Finger 3
Chromosome: CHR3: 73431651 -73674072
Locus: 3p13
TMC1 Gene Summary
This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness. [provided by RefSeq, Jul 2008]
Gene Name: Transmembrane Channel Like 1
Chromosome: CHR9: 75136716 -75451267
Locus: 9q21.13
Gene Diseases
The PDZRN3 TMC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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