PDZRN3-EIF4E3 Fusion FISH Probe
The PDZRN3-EIF4E3 Fusion FISH Probe is used to confirm a fusion of the PDZRN3 and EIF4E3 genes. The fusion of the PDZRN3 and EIF4E3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDZRN3-EIF4E3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-RERE | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-REOR | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-REGO | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-REGR | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-REAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-ORRE | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-OROR | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-ORGO | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GORE | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GOOR | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GOGO | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GOGR | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GRRE | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GROR | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GRGO | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GRGR | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-AQRE | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-AQOR | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-AQGO | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-AQGR | 20 (40 μL) | 200 μL |
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| PDZRN3-EIF4E3-20-AQAQ | 20 (40 μL) | 200 μL |
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PDZRN3 Gene Summary
This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: PDZ Domain Containing Ring Finger 3
Chromosome: CHR3: 73431651 -73674072
Locus: 3p13
EIF4E3 Gene Summary
EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008]
Gene Name: Eukaryotic Translation Initiation Factor 4E Family Member 3
Chromosome: CHR3: 71728439 -71803924
Locus: 3p13
Gene Diseases
The PDZRN3 EIF4E3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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