PDZRN3-ADAM19 Fusion FISH Probe
The PDZRN3-ADAM19 Fusion FISH Probe is used to confirm a fusion of the PDZRN3 and ADAM19 genes. The fusion of the PDZRN3 and ADAM19 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDZRN3-ADAM19-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-RERE | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-REOR | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-REGO | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-REGR | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-REAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-ORRE | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-OROR | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-ORGO | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GORE | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GOOR | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GOGO | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GOGR | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GRRE | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GROR | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GRGO | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GRGR | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-AQRE | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-AQOR | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-AQGO | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-AQGR | 20 (40 μL) | 200 μL |
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| PDZRN3-ADAM19-20-AQAQ | 20 (40 μL) | 200 μL |
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ADAM19 Gene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013]
Gene Name: ADAM Metallopeptidase Domain 19
Chromosome: CHR5: 156904311 -157002783
Locus: 5q33.3
PDZRN3 Gene Summary
This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: PDZ Domain Containing Ring Finger 3
Chromosome: CHR3: 73431651 -73674072
Locus: 3p13
Gene Diseases
The PDZRN3 ADAM19 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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