PDS5B-UBR2 Fusion FISH Probe
The PDS5B-UBR2 Fusion FISH Probe is used to confirm a fusion of the PDS5B and UBR2 genes. The fusion of the PDS5B and UBR2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDS5B-UBR2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-RERE | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-REOR | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-REGO | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-REGR | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-REAQ | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-ORRE | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-OROR | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-ORGO | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GORE | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GOOR | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GOGO | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GOGR | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GRRE | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GROR | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GRGO | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GRGR | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-AQRE | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-AQOR | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-AQGO | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-AQGR | 20 (40 μL) | 200 μL |
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| PDS5B-UBR2-20-AQAQ | 20 (40 μL) | 200 μL |
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PDS5B Gene Summary
This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq, Jul 2015]
Gene Name: PDS5 Cohesin Associated Factor B
Chromosome: CHR13: 33160563 -33352158
Locus: 13q13.1
UBR2 Gene Summary
This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Ubiquitin Protein Ligase E3 Component N-recognin 2
Chromosome: CHR6: 42531759 -42661243
Locus: 6p21.1
Gene Diseases
The PDS5B UBR2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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