PDPK1-CCNF Fusion FISH Probe
The PDPK1-CCNF Fusion FISH Probe is used to confirm a fusion of the PDPK1 and CCNF genes. The fusion of the PDPK1 and CCNF genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDPK1-CCNF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-RERE | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-REOR | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-REGO | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-REGR | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-REAQ | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-ORRE | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-OROR | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-ORGO | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GORE | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GOOR | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GOGO | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GOGR | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GRRE | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GROR | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GRGO | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GRGR | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-AQRE | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-AQOR | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-AQGO | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-AQGR | 20 (40 μL) | 200 μL |
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| PDPK1-CCNF-20-AQAQ | 20 (40 μL) | 200 μL |
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CCNF Gene Summary
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008]
Gene Name: Cyclin F
Chromosome: CHR16: 2479394 -2508859
Locus: 16p13.3
PDPK1 Gene Summary
The 3-phosphoinositide Dependent Protein Kinase 1 (PDPK1) gene is located on chr16 :2587969-2653189 at 16p13.3.
Gene Name: 3-phosphoinositide Dependent Protein Kinase 1
Chromosome: CHR16: 2587969 -2653189
Locus: 16p13.3
Gene Diseases
The PDPK1 CCNF Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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