PDLIM7-FAM193B Fusion FISH Probe
The PDLIM7-FAM193B Fusion FISH Probe is used to confirm a fusion of the PDLIM7 and FAM193B genes. The fusion of the PDLIM7 and FAM193B genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDLIM7-FAM193B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-RERE | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-REOR | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-REGO | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-REGR | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-REAQ | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-ORRE | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-OROR | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-ORGO | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GORE | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GOOR | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GOGO | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GOGR | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GRRE | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GROR | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GRGO | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GRGR | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-AQRE | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-AQOR | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-AQGO | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-AQGR | 20 (40 μL) | 200 μL |
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| PDLIM7-FAM193B-20-AQAQ | 20 (40 μL) | 200 μL |
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PDLIM7 Gene Summary
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: PDZ And LIM Domain 7
Chromosome: CHR5: 176910394 -176924602
Locus: 5q35.3
FAM193B Gene Summary
The Family With Sequence Similarity 193 Member B (FAM193B) gene is located on chr5 :176946789-176981548 at 5q35.3.
Gene Name: Family With Sequence Similarity 193 Member B
Chromosome: CHR5: 176946789 -176981548
Locus: 5q35.3
Gene Diseases
The PDLIM7 FAM193B Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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