PDLIM5-ART3 Fusion FISH Probe
The PDLIM5-ART3 Fusion FISH Probe is used to confirm a fusion of the PDLIM5 and ART3 genes. The fusion of the PDLIM5 and ART3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDLIM5-ART3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-RERE | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-REOR | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-REGO | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-REGR | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-REAQ | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-ORRE | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-OROR | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-ORGO | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GORE | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GOOR | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GOGO | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GOGR | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GRRE | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GROR | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GRGO | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GRGR | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-AQRE | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-AQOR | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-AQGO | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-AQGR | 20 (40 μL) | 200 μL |
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| PDLIM5-ART3-20-AQAQ | 20 (40 μL) | 200 μL |
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ART3 Gene Summary
This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: ADP-ribosyltransferase 3
Chromosome: CHR4: 76932336 -77033955
Locus: 4p15.1-p14
PDLIM5 Gene Summary
This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Name: PDZ And LIM Domain 5
Chromosome: CHR4: 95373037 -95589377
Locus: 4q22.3
Gene Diseases
The PDLIM5 ART3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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