PDLIM1-SORBS1 Fusion FISH Probe
The PDLIM1-SORBS1 Fusion FISH Probe is used to confirm a fusion of the PDLIM1 and SORBS1 genes. The fusion of the PDLIM1 and SORBS1 genes has been associated with Lung Adenocarcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDLIM1-SORBS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-RERE | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-REOR | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-REGO | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-REGR | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-REAQ | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-ORRE | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-OROR | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-ORGO | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GORE | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GOOR | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GOGO | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GOGR | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GRRE | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GROR | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GRGO | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GRGR | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-AQRE | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-AQOR | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-AQGO | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-AQGR | 20 (40 μL) | 200 μL |
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| PDLIM1-SORBS1-20-AQAQ | 20 (40 μL) | 200 μL |
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PDLIM1 Gene Summary
This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. [provided by RefSeq, Oct 2012]
Gene Name: PDZ And LIM Domain 1
Chromosome: CHR10: 96997329 -97050781
Locus: 10q23.33
SORBS1 Gene Summary
This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Name: Sorbin And SH3 Domain Containing 1
Chromosome: CHR10: 97071529 -97321171
Locus: 10q24.1
Gene Diseases
The PDLIM1 SORBS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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