PDIA4-HACE1 Fusion FISH Probe
The PDIA4-HACE1 Fusion FISH Probe is used to confirm a fusion of the PDIA4 and HACE1 genes. The fusion of the PDIA4 and HACE1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDIA4-HACE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-RERE | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-REOR | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-REGO | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-REGR | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-REAQ | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-ORRE | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-OROR | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-ORGO | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GORE | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GOOR | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GOGO | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GOGR | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GRRE | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GROR | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GRGO | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GRGR | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-AQRE | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-AQOR | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-AQGO | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-AQGR | 20 (40 μL) | 200 μL |
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| PDIA4-HACE1-20-AQAQ | 20 (40 μL) | 200 μL |
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PDIA4 Gene Summary
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. This protein, when bound to cyclophilin B, enhances the rate of immunoglobulin G intermolecular disulfide bonding and antibody assembly. [provided by RefSeq, Dec 2016]
Gene Name: Protein Disulfide Isomerase Family A Member 4
Chromosome: CHR7: 148700153 -148725782
Locus: 7q36.1
HACE1 Gene Summary
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]
Gene Name: HECT Domain And Ankyrin Repeat Containing E3 Ubiquitin Protein Ligase 1
Chromosome: CHR6: 105175967 -105307794
Locus: 6q16.3
Gene Diseases
The PDIA4 HACE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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