PDE9A-ABCG1 Fusion FISH Probe
The PDE9A-ABCG1 Fusion FISH Probe is used to confirm a fusion of the PDE9A and ABCG1 genes. The fusion of the PDE9A and ABCG1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDE9A-ABCG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-RERE | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-REOR | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-REGO | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-REGR | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-REAQ | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-ORRE | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-OROR | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-ORGO | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GORE | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GOOR | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GOGO | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GOGR | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GRRE | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GROR | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GRGO | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GRGR | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-AQRE | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-AQOR | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-AQGO | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-AQGR | 20 (40 μL) | 200 μL |
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| PDE9A-ABCG1-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE9A Gene Summary
The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Phosphodiesterase 9A
Chromosome: CHR21: 44073861 -44195618
Locus: 21q22.3
ABCG1 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily G Member 1
Chromosome: CHR21: 43619798 -43717354
Locus: 21q22.3
Gene Diseases
The PDE9A ABCG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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