PDE4D-RAB24 Fusion FISH Probe
The PDE4D-RAB24 Fusion FISH Probe is used to confirm a fusion of the PDE4D and RAB24 genes. The fusion of the PDE4D and RAB24 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDE4D-RAB24-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-RERE | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-REOR | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-REGO | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-REGR | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-REAQ | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-ORRE | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-OROR | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-ORGO | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GORE | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GOOR | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GOGO | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GOGR | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GRRE | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GROR | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GRGO | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GRGR | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-AQRE | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-AQOR | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-AQGO | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-AQGR | 20 (40 μL) | 200 μL |
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| PDE4D-RAB24-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE4D Gene Summary
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
Gene Name: Phosphodiesterase 4D
Chromosome: CHR5: 58264865 -59783925
Locus: 5q11.2-q12.1
RAB24 Gene Summary
RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009]
Gene Name: RAB24, Member RAS Oncogene Family
Chromosome: CHR5: 176728198 -176730744
Locus: 5q35.3
Gene Diseases
The PDE4D RAB24 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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