PDE4D-DEPDC1B Fusion FISH Probe
The PDE4D-DEPDC1B Fusion FISH Probe is used to confirm a fusion of the PDE4D and DEPDC1B genes. The fusion of the PDE4D and DEPDC1B genes has been associated with Lung Squamous Cell Carcinoma, Lung Adenocarcinoma, Lung Squamous Cell Carcinoma, Prostate Adenocarcinoma, Prostate Adenocarcinoma, Prostate Adenocarcinoma, and Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDE4D-DEPDC1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-RERE | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-REOR | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-REGO | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-REGR | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-REAQ | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-ORRE | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-OROR | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-ORGO | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GORE | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GOOR | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GOGO | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GOGR | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GRRE | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GROR | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GRGO | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GRGR | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-AQRE | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-AQOR | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-AQGO | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-AQGR | 20 (40 μL) | 200 μL |
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| PDE4D-DEPDC1B-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE4D Gene Summary
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
Gene Name: Phosphodiesterase 4D
Chromosome: CHR5: 58264865 -59783925
Locus: 5q11.2-q12.1
DEPDC1B Gene Summary
The DEP Domain Containing 1B (DEPDC1B) gene is located on chr5 :59892738-59995993 at 5q12.1.
Gene Name: DEP Domain Containing 1B
Chromosome: CHR5: 59892738 -59995993
Locus: 5q12.1
Gene Diseases
The PDE4D DEPDC1B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Lung Adenocarcinoma |
| Lung Squamous Cell Carcinoma |
| Prostate Adenocarcinoma |
| Prostate Adenocarcinoma |
| Prostate Adenocarcinoma |
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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