PDE4D-CRABP1 Fusion FISH Probe
The PDE4D-CRABP1 Fusion FISH Probe is used to confirm a fusion of the PDE4D and CRABP1 genes. The fusion of the PDE4D and CRABP1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDE4D-CRABP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-RERE | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-REOR | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-REGO | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-REGR | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-OROR | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GORE | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GROR | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PDE4D-CRABP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CRABP1 Gene Summary
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. [provided by RefSeq, Jul 2008]
Gene Name: Cellular Retinoic Acid Binding Protein 1
Chromosome: CHR15: 78632665 -78640572
Locus: 15q25.1
PDE4D Gene Summary
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
Gene Name: Phosphodiesterase 4D
Chromosome: CHR5: 58264865 -59783925
Locus: 5q11.2-q12.1
Gene Diseases
The PDE4D CRABP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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