PDE3B-MICAL2 Fusion FISH Probe
The PDE3B-MICAL2 Fusion FISH Probe is used to confirm a fusion of the PDE3B and MICAL2 genes. The fusion of the PDE3B and MICAL2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDE3B-MICAL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-RERE | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-REOR | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-REGO | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-REGR | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-REAQ | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-ORRE | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-OROR | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-ORGO | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GORE | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GOOR | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GOGO | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GOGR | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GRRE | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GROR | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GRGO | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GRGR | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-AQRE | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-AQOR | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-AQGO | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-AQGR | 20 (40 μL) | 200 μL |
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| PDE3B-MICAL2-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE3B Gene Summary
The Phosphodiesterase 3B (PDE3B) gene is located on chr11 :14665268-14893604 at 11p15.2.
Gene Name: Phosphodiesterase 3B
Chromosome: CHR11: 14665268 -14893604
Locus: 11p15.2
MICAL2 Gene Summary
The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
Gene Name: Microtubule Associated Monooxygenase, Calponin And LIM Domain Containing 2
Chromosome: CHR11: 12132137 -12285331
Locus: 11p15.3
Gene Diseases
The PDE3B MICAL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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