PDE12-KCNJ4 Fusion FISH Probe
The PDE12-KCNJ4 Fusion FISH Probe is used to confirm a fusion of the PDE12 and KCNJ4 genes. The fusion of the PDE12 and KCNJ4 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDE12-KCNJ4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-RERE | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-REOR | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-REGO | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-REGR | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-REAQ | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-ORRE | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-OROR | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-ORGO | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GORE | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GOOR | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GOGO | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GOGR | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GRRE | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GROR | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GRGO | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GRGR | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-AQRE | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-AQOR | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-AQGO | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-AQGR | 20 (40 μL) | 200 μL |
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| PDE12-KCNJ4-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNJ4 Gene Summary
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Voltage-gated Channel Subfamily J Member 4
Chromosome: CHR22: 38822332 -38851203
Locus: 22q13.1
PDE12 Gene Summary
The Phosphodiesterase 12 (PDE12) gene is located on chr3 :57541980-57547768 at 3p14.3.
Gene Name: Phosphodiesterase 12
Chromosome: CHR3: 57541980 -57547768
Locus: 3p14.3
Gene Diseases
The PDE12 KCNJ4 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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