PDCL-NCS1 Fusion FISH Probe
The PDCL-NCS1 Fusion FISH Probe is used to confirm a fusion of the PDCL and NCS1 genes. The fusion of the PDCL and NCS1 genes has been associated with Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDCL-NCS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-RERE | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-REOR | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-REGO | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-REGR | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-REAQ | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-ORRE | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-OROR | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-ORGO | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GORE | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GOOR | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GOGO | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GOGR | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GRRE | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GROR | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GRGO | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GRGR | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-AQRE | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-AQOR | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-AQGO | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-AQGR | 20 (40 μL) | 200 μL |
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| PDCL-NCS1-20-AQAQ | 20 (40 μL) | 200 μL |
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PDCL Gene Summary
Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]
Gene Name: Phosducin Like
Chromosome: CHR9: 125580375 -125590935
Locus: 9q33.2
NCS1 Gene Summary
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Neuronal Calcium Sensor 1
Chromosome: CHR9: 132934856 -132999583
Locus: 9q34.11
Gene Diseases
The PDCL NCS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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