PCMTD1-MRPL15 Fusion FISH Probe
The PCMTD1-MRPL15 Fusion FISH Probe is used to confirm a fusion of the PCMTD1 and MRPL15 genes. The fusion of the PCMTD1 and MRPL15 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PCMTD1-MRPL15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-RERE | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-REOR | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-REGO | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-REGR | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-REAQ | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-ORRE | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-OROR | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-ORGO | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-ORAQ | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GORE | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GOOR | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GOGO | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GOGR | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GOAQ | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GRRE | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GROR | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GRGO | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GRGR | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-GRAQ | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-AQRE | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-AQOR | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-AQGO | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-AQGR | 20 (40 μL) | 200 μL |
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| PCMTD1-MRPL15-20-AQAQ | 20 (40 μL) | 200 μL |
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MRPL15 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein L15
Chromosome: CHR8: 55047780 -55061074
Locus: 8q11.23
PCMTD1 Gene Summary
The Protein-L-isoaspartate (D-aspartate) O-methyltransferase Domain Containing 1 (PCMTD1) gene is located on chr8 :52730139-52811735 at 8q11.23.
Gene Name: Protein-L-isoaspartate (D-aspartate) O-methyltransferase Domain Containing 1
Chromosome: CHR8: 52730139 -52811735
Locus: 8q11.23
Gene Diseases
The PCMTD1 MRPL15 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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