PCID2-SNRPA Fusion FISH Probe
The PCID2-SNRPA Fusion FISH Probe is used to confirm a fusion of the PCID2 and SNRPA genes. The fusion of the PCID2 and SNRPA genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PCID2-SNRPA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-RERE | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-REOR | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-REGO | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-REGR | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-REAQ | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-ORRE | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-OROR | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-ORGO | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-ORAQ | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GORE | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GOOR | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GOGO | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GOGR | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GOAQ | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GRRE | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GROR | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GRGO | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GRGR | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-GRAQ | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-AQRE | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-AQOR | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-AQGO | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-AQGR | 20 (40 μL) | 200 μL |
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| PCID2-SNRPA-20-AQAQ | 20 (40 μL) | 200 μL |
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SNRPA Gene Summary
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. [provided by RefSeq, Oct 2010]
Gene Name: Small Nuclear Ribonucleoprotein Polypeptide A
Chromosome: CHR19: 41256758 -41271297
Locus: 19q13.2
PCID2 Gene Summary
This gene encodes a component of the TREX-2 complex (transcription and export complex 2), which regulates mRNA export from the nucleus. This protein regulates expression of Mad2 mitotic arrest deficient-like 1, a cell division checkpoint protein. This protein also interacts with and stabilizes Brca2 (breast cancer 2) protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: PCI Domain Containing 2
Chromosome: CHR13: 113831924 -113863029
Locus: 13q34
Gene Diseases
The PCID2 SNRPA Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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