PCF11-DOCK2 Fusion FISH Probe
The PCF11-DOCK2 Fusion FISH Probe is used to confirm a fusion of the PCF11 and DOCK2 genes. The fusion of the PCF11 and DOCK2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PCF11-DOCK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PCF11-DOCK2-20-AQAQ | 20 (40 μL) | 200 μL |
|
DOCK2 Gene Summary
The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016]
Gene Name: Dedicator Of Cytokinesis 2
Chromosome: CHR5: 169064250 -169510386
Locus: 5q35.1
PCF11 Gene Summary
The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage. [provided by RefSeq, Oct 2016]
Gene Name: PCF11 Cleavage And Polyadenylation Factor Subunit
Chromosome: CHR11: 82868136 -82896835
Locus: 11q14.1
Gene Diseases
The PCF11 DOCK2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|