PCBP3-GRIK1 Fusion FISH Probe
The PCBP3-GRIK1 Fusion FISH Probe is used to confirm a fusion of the PCBP3 and GRIK1 genes. The fusion of the PCBP3 and GRIK1 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PCBP3-GRIK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-RERE | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-REOR | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-REGO | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-REGR | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-REAQ | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-ORRE | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-OROR | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-ORGO | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GORE | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GOOR | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GOGO | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GOGR | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GRRE | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GROR | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GRGO | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GRGR | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-AQRE | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-AQOR | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-AQGO | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-AQGR | 20 (40 μL) | 200 μL |
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| PCBP3-GRIK1-20-AQAQ | 20 (40 μL) | 200 μL |
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GRIK1 Gene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Glutamate Ionotropic Receptor Kainate Type Subunit 1
Chromosome: CHR21: 30909253 -31312282
Locus: 21q21.3
PCBP3 Gene Summary
This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. The protein encoded by this gene lacks the nuclear localization signals found in other subfamily members. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017]
Gene Name: Poly(rC) Binding Protein 3
Chromosome: CHR21: 47269874 -47362368
Locus: 21q22.3
Gene Diseases
The PCBP3 GRIK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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