PC-ORAOV1 Fusion FISH Probe
The PC-ORAOV1 Fusion FISH Probe is used to confirm a fusion of the PC and ORAOV1 genes. The fusion of the PC and ORAOV1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PC-ORAOV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-RERE | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-REOR | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-REGO | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-REGR | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-REAQ | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-ORRE | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-OROR | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-ORGO | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GORE | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GOOR | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GOGO | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GOGR | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GRRE | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GROR | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GRGO | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GRGR | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-AQRE | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-AQOR | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-AQGO | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-AQGR | 20 (40 μL) | 200 μL |
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| PC-ORAOV1-20-AQAQ | 20 (40 μL) | 200 μL |
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PC Gene Summary
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Pyruvate Carboxylase
Chromosome: CHR11: 66615996 -66725847
Locus: 11q13.2
ORAOV1 Gene Summary
The Oral Cancer Overexpressed 1 (ORAOV1) gene is located on chr11 :69480331-69490165 at 11q13.3.
Gene Name: Oral Cancer Overexpressed 1
Chromosome: CHR11: 69480331 -69490165
Locus: 11q13.3
Gene Diseases
The PC ORAOV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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