PBRM1-IGSF11 Fusion FISH Probe
The PBRM1-IGSF11 Fusion FISH Probe is used to confirm a fusion of the PBRM1 and IGSF11 genes. The fusion of the PBRM1 and IGSF11 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PBRM1-IGSF11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-RERE | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-REOR | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-REGO | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-REGR | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-REAQ | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-ORRE | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-OROR | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-ORGO | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-ORAQ | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GORE | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GOOR | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GOGO | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GOGR | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GOAQ | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GRRE | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GROR | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GRGO | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GRGR | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-GRAQ | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-AQRE | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-AQOR | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-AQGO | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-AQGR | 20 (40 μL) | 200 μL |
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| PBRM1-IGSF11-20-AQAQ | 20 (40 μL) | 200 μL |
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PBRM1 Gene Summary
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]
Gene Name: Polybromo 1
Chromosome: CHR3: 52579367 -52719866
Locus: 3p21.1
IGSF11 Gene Summary
IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).[supplied by OMIM, Apr 2005]
Gene Name: Immunoglobulin Superfamily Member 11
Chromosome: CHR3: 118619478 -118864898
Locus: 3q13.32
Gene Diseases
The PBRM1 IGSF11 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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