PAWR-CLEC2A Fusion FISH Probe
The PAWR-CLEC2A Fusion FISH Probe is used to confirm a fusion of the PAWR and CLEC2A genes. The fusion of the PAWR and CLEC2A genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PAWR-CLEC2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-RERE | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-REOR | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-REGO | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-REGR | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-REAQ | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-ORRE | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-OROR | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-ORGO | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GORE | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GOOR | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GOGO | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GOGR | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GRRE | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GROR | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GRGO | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GRGR | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-AQRE | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-AQOR | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-AQGO | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-AQGR | 20 (40 μL) | 200 μL |
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| PAWR-CLEC2A-20-AQAQ | 20 (40 μL) | 200 μL |
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PAWR Gene Summary
This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017]
Gene Name: Pro-apoptotic WT1 Regulator
Chromosome: CHR12: 79985744 -80084790
Locus: 12q21.2
CLEC2A Gene Summary
CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).[supplied by OMIM, May 2008]
Gene Name: C-type Lectin Domain Family 2 Member A
Chromosome: CHR12: 10065825 -10084980
Locus: 12p13.31
Gene Diseases
The PAWR CLEC2A Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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