PASK-BOK Fusion FISH Probe
The PASK-BOK Fusion FISH Probe is used to confirm a fusion of the PASK and BOK genes. The fusion of the PASK and BOK genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PASK-BOK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-RERE | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-REOR | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-REGO | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-REGR | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-REAQ | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-ORRE | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-OROR | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-ORGO | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-ORAQ | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GORE | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GOOR | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GOGO | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GOGR | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GOAQ | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GRRE | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GROR | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GRGO | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GRGR | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-GRAQ | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-AQRE | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-AQOR | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-AQGO | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-AQGR | 20 (40 μL) | 200 μL |
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| PASK-BOK-20-AQAQ | 20 (40 μL) | 200 μL |
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BOK Gene Summary
The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011]
Gene Name: BOK, BCL2 Family Apoptosis Regulator
Chromosome: CHR2: 242498191 -242513553
Locus: 2q37.3
PASK Gene Summary
This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Gene Name: PAS Domain Containing Serine/threonine Kinase
Chromosome: CHR2: 242045514 -242088878
Locus: 2q37.3
Gene Diseases
The PASK BOK Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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