PASD1-ZFX Fusion FISH Probe
The PASD1-ZFX Fusion FISH Probe is used to confirm a fusion of the PASD1 and ZFX genes. The fusion of the PASD1 and ZFX genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PASD1-ZFX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PASD1-ZFX-20-AQAQ | 20 (40 μL) | 200 μL |
|
ZFX Gene Summary
This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2010]
Gene Name: Zinc Finger Protein, X-linked
Chromosome: CHRX: 24167761 -24234372
Locus: Xp22.11
PASD1 Gene Summary
This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010]
Gene Name: PAS Domain Containing Repressor 1
Chromosome: CHRX: 150732006 -150845211
Locus: Xq28
Gene Diseases
The PASD1 ZFX Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|