PARD3-IL2RA Fusion FISH Probe
The PARD3-IL2RA Fusion FISH Probe is used to confirm a fusion of the PARD3 and IL2RA genes. The fusion of the PARD3 and IL2RA genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PARD3-IL2RA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-RERE | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-REOR | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-REGO | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-REGR | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-REAQ | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-ORRE | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-OROR | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-ORGO | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-ORAQ | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GORE | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GOOR | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GOGO | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GOGR | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GOAQ | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GRRE | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GROR | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GRGO | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GRGR | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-GRAQ | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-AQRE | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-AQOR | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-AQGO | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-AQGR | 20 (40 μL) | 200 μL |
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| PARD3-IL2RA-20-AQAQ | 20 (40 μL) | 200 μL |
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IL2RA Gene Summary
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
Gene Name: Interleukin 2 Receptor Subunit Alpha
Chromosome: CHR10: 6052656 -6104333
Locus: 10p15.1
PARD3 Gene Summary
This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Par-3 Family Cell Polarity Regulator
Chromosome: CHR10: 34398487 -35104253
Locus: 10p11.22-p11.21
Gene Diseases
The PARD3 IL2RA Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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