PAPSS2-SFRP5 Fusion FISH Probe
The PAPSS2-SFRP5 Fusion FISH Probe is used to confirm a fusion of the PAPSS2 and SFRP5 genes. The fusion of the PAPSS2 and SFRP5 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PAPSS2-SFRP5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-RERE | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-REOR | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-REGO | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-REGR | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-REAQ | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-ORRE | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-OROR | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-ORGO | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-ORAQ | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GORE | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GOOR | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GOGO | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GOGR | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GOAQ | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GRRE | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GROR | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GRGO | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GRGR | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-GRAQ | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-AQRE | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-AQOR | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-AQGO | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-AQGR | 20 (40 μL) | 200 μL |
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| PAPSS2-SFRP5-20-AQAQ | 20 (40 μL) | 200 μL |
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SFRP5 Gene Summary
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq, Jul 2008]
Gene Name: Secreted Frizzled Related Protein 5
Chromosome: CHR10: 99526507 -99531756
Locus: 10q24.2
PAPSS2 Gene Summary
Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: 3'-phosphoadenosine 5'-phosphosulfate Synthase 2
Chromosome: CHR10: 89419475 -89507462
Locus: 10q23.2-q23.31
Gene Diseases
The PAPSS2 SFRP5 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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