PAPSS2-BID Fusion FISH Probe
The PAPSS2-BID Fusion FISH Probe is used to confirm a fusion of the PAPSS2 and BID genes. The fusion of the PAPSS2 and BID genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAPSS2-BID-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PAPSS2-BID-20-AQAQ | 20 (40 μL) | 200 μL |
|
BID Gene Summary
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Gene Name: BH3 Interacting Domain Death Agonist
Chromosome: CHR22: 18216905 -18257258
Locus: 22q11.21
PAPSS2 Gene Summary
Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: 3'-phosphoadenosine 5'-phosphosulfate Synthase 2
Chromosome: CHR10: 89419475 -89507462
Locus: 10q23.2-q23.31
Gene Diseases
The PAPSS2 BID Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|