PAPPA2-ASTN1 Fusion FISH Probe
The PAPPA2-ASTN1 Fusion FISH Probe is used to confirm a fusion of the PAPPA2 and ASTN1 genes. The fusion of the PAPPA2 and ASTN1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PAPPA2-ASTN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-RERE | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-REOR | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-REGO | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-REGR | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-REAQ | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-ORRE | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-OROR | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-ORGO | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GORE | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GOOR | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GOGO | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GOGR | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GRRE | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GROR | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GRGO | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GRGR | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-AQRE | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-AQOR | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-AQGO | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-AQGR | 20 (40 μL) | 200 μL |
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| PAPPA2-ASTN1-20-AQAQ | 20 (40 μL) | 200 μL |
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ASTN1 Gene Summary
Astrotactin is a neuronal adhesion molecule required for glial-guided migration of young postmitotic neuroblasts in cortical regions of developing brain, including cerebrum, hippocampus, cerebellum, and olfactory bulb (Fink et al., 1995).[supplied by OMIM, Jun 2009]
Gene Name: Astrotactin 1
Chromosome: CHR1: 176830202 -177134024
Locus: 1q25.2
PAPPA2 Gene Summary
This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Gene Name: Pappalysin 2
Chromosome: CHR1: 176432306 -176811970
Locus: 1q25.2
Gene Diseases
The PAPPA2 ASTN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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