PAPOLG-ABCA12 Fusion FISH Probe
The PAPOLG-ABCA12 Fusion FISH Probe is used to confirm a fusion of the PAPOLG and ABCA12 genes. The fusion of the PAPOLG and ABCA12 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAPOLG-ABCA12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PAPOLG-ABCA12-20-AQAQ | 20 (40 μL) | 200 μL |
|
ABCA12 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily A Member 12
Chromosome: CHR2: 215796265 -216003151
Locus: 2q35
PAPOLG Gene Summary
This gene encodes a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60% identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity. This gene is located on chromosome 2 in contrast to the PAPII gene, which is located on chromosome 14. [provided by RefSeq, Jul 2008]
Gene Name: Poly(A) Polymerase Gamma
Chromosome: CHR2: 60983364 -61029221
Locus: 2p16.1
Gene Diseases
The PAPOLG ABCA12 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|