PANK4-RGS6 Fusion FISH Probe
The PANK4-RGS6 Fusion FISH Probe is used to confirm a fusion of the PANK4 and RGS6 genes. The fusion of the PANK4 and RGS6 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PANK4-RGS6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-RERE | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-REOR | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-REGO | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-REGR | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-REAQ | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-ORRE | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-OROR | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-ORGO | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-ORAQ | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GORE | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GOOR | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GOGO | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GOGR | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GOAQ | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GRRE | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GROR | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GRGO | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GRGR | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-GRAQ | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-AQRE | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-AQOR | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-AQGO | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-AQGR | 20 (40 μL) | 200 μL |
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| PANK4-RGS6-20-AQAQ | 20 (40 μL) | 200 μL |
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RGS6 Gene Summary
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]
Gene Name: Regulator Of G Protein Signaling 6
Chromosome: CHR14: 72398816 -73033238
Locus: 14q24.2
PANK4 Gene Summary
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. [provided by RefSeq, Jul 2008]
Gene Name: Pantothenate Kinase 4
Chromosome: CHR1: 2439974 -2458035
Locus: 1p36.32
Gene Diseases
The PANK4 RGS6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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