PANK2-LANCL1 Fusion FISH Probe
The PANK2-LANCL1 Fusion FISH Probe is used to confirm a fusion of the PANK2 and LANCL1 genes. The fusion of the PANK2 and LANCL1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PANK2-LANCL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-RERE | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-REOR | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-REGO | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-REGR | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-REAQ | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-ORRE | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-OROR | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-ORGO | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GORE | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GOOR | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GOGO | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GOGR | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GRRE | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GROR | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GRGO | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GRGR | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-AQRE | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-AQOR | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-AQGO | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-AQGR | 20 (40 μL) | 200 μL |
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| PANK2-LANCL1-20-AQAQ | 20 (40 μL) | 200 μL |
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LANCL1 Gene Summary
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Gene Name: LanC Like 1
Chromosome: CHR2: 211295972 -211341499
Locus: 2q34
PANK2 Gene Summary
This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Pantothenate Kinase 2
Chromosome: CHR20: 3869485 -3904502
Locus: 20p13
Gene Diseases
The PANK2 LANCL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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