PAN3-LATS2 Fusion FISH Probe
The PAN3-LATS2 Fusion FISH Probe is used to confirm a fusion of the PAN3 and LATS2 genes. The fusion of the PAN3 and LATS2 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PAN3-LATS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-RERE | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-REOR | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-REGO | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-REGR | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-REAQ | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-ORRE | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-OROR | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-ORGO | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GORE | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GOOR | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GOGO | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GOGR | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GRRE | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GROR | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GRGO | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GRGR | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-AQRE | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-AQOR | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-AQGO | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-AQGR | 20 (40 μL) | 200 μL |
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| PAN3-LATS2-20-AQAQ | 20 (40 μL) | 200 μL |
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LATS2 Gene Summary
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
Gene Name: Large Tumor Suppressor Kinase 2
Chromosome: CHR13: 21547175 -21635722
Locus: 13q12.11
PAN3 Gene Summary
The PAN3 Poly(A) Specific Ribonuclease Subunit (PAN3) gene is located on chr13 :28712642-28869475 at 13q12.2.
Gene Name: PAN3 Poly(A) Specific Ribonuclease Subunit
Chromosome: CHR13: 28712642 -28869475
Locus: 13q12.2
Gene Diseases
The PAN3 LATS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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