PAN2-MIP Fusion FISH Probe
The PAN2-MIP Fusion FISH Probe is used to confirm a fusion of the PAN2 and MIP genes. The fusion of the PAN2 and MIP genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PAN2-MIP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-RERE | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-REOR | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-REGO | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-REGR | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-REAQ | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-ORRE | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-OROR | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-ORGO | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-ORAQ | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GORE | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GOOR | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GOGO | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GOGR | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GOAQ | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GRRE | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GROR | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GRGO | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GRGR | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-GRAQ | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-AQRE | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-AQOR | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-AQGO | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-AQGR | 20 (40 μL) | 200 μL |
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| PAN2-MIP-20-AQAQ | 20 (40 μL) | 200 μL |
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MIP Gene Summary
Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13. [provided by RefSeq, Jul 2008]
Gene Name: Major Intrinsic Protein Of Lens Fiber
Chromosome: CHR12: 56843285 -56848435
Locus: 12q13.3
PAN2 Gene Summary
This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: PAN2 Poly(A) Specific Ribonuclease Subunit
Chromosome: CHR12: 56710006 -56727837
Locus: 12q13.3
Gene Diseases
The PAN2 MIP Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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